Chen Yu

Chief Physician

Good at comprehensive treatment of malignant bone tumor and soft tissue tumor with limb salvage surgery combined with radiotherapy and chemotherapy, intraoperative radiotherapy, melanoma and other skin cancer surgery and comprehensive treatment, as well as bone metastatic cancer surgery and comprehensive treatment.

Introduction of the expert

Chen Yu, Director of Orthopaedic and Soft Surgery Department, Chief Physician, High Level Talent (Category D), Hainan Province, holds a Masters degree in Orthopedic Surgery from the Medical School of Nanchang University and has over 30 years of clinical experience in the field of orthopedics, established the only Orthopedics Department in Hainan Province, filling the gap in bone and soft tissue tumors in Hainan Province. During this period, led the team to carry out a number of difficult operations, and took the lead in carrying out the first case of tumor resection + intraoperative radiotherapy + reconstruction of bone metastatic cancer and the first case of extended resection + intraoperative radiotherapy + skin grafting of soft tissue sarcoma of limbs in Hainan Province. 
Participated in 1 national 863 project, presided over 1 provincial and ministerial level project, 3 projects of Provincial Health Department, and 1 provincial natural science fund project. Has published more than 20 papers, including 2 in Chinese core journals and 4 in SCI.

Medical specialty

I. Specializes in limb-salvage surgery for malignant bone tumors and soft tissue tumors, combining comprehensive treatments such as radiotherapy, chemotherapy, and intraoperative radiation therapy 
II. Surgeries and comprehensive treatments for skin cancers such as melanoma 
III. Surgeries and comprehensive treatments for bone metastasis cancers 
IV. Treatment of various conditions including trauma, burns, joint disorders, spinal conditions, and bone diseases

Direction of scientific research

Bone tumor, soft tissue tumor, skin tumor, bone metastatic cancer.

Academic association appointment

Currently served as: 
Ⅰ. Chairman of the Bone and Soft Tissue Tumor Professional Committee of Hainan Cancer Prevention and Treatment Association 
Ⅱ. Vice Chairman of Wound Repair Branch of Hainan Medical Association 
Ⅲ. Vice Chairman of Central South Bone Cancer Alliance of China Cancer Prevention Alliance 
Ⅳ. Standing Committee of Bone and Soft Tissue Oncology Group, Special Committee for Minimally Invasive Tumor Therapy, China Anti-Cancer Association 
Ⅴ. National member of Sarcoma Professional Committee of China Anti-Cancer Association 
Ⅵ. National member of Melanoma Professional Committee of China Anti-Cancer Association 
Ⅶ. National member of the Skin Cancer Professional Committee of China Anti-Cancer Association 
Ⅷ. National member of Bone and Soft Tissue Tumor Professional Committee, Chinese Medical Education Association 
Ⅸ. National member of Chemoradiotherapy Group, Sarcoma Professional Committee, China Anti-Cancer Association 
Ⅹ. Member of Orthopaedic Branch of Hainan Medical Association 
Ⅺ. Member of Pediatric Surgery Branch of Hainan Medical Association  
Once served as: 
Ⅰ. Member of the 9th National Youth Committee of Orthopaedic Branch of Chinese Medical Association 
Ⅱ. National member of SICOT Chinese Digital Orthopaedic Association, International Society for Orthopaedic and Trauma Surgery  
Ⅲ. Member of the First Sports Medicine Professional Committee of Hainan Medical Association 
Ⅳ. Member of Hand Surgery Branch of Hainan Medical Association 

Papers and works

1. ZONGQUAN XU, CHEN YU, SHUFANG WANG, and GUOHUI XU1, Transcatheter arterial chemoembolization as an examination method for hepatocellular carcinoma undetected by B-mode ultrasound, computed tomography and digital subtratcion angiography: A case report. Oncol Lett. 2015 Sep; 10(3): 1759–1762.

2.Zongquan Xu, Yu Chen, Guohui Xu, Cheng Peng, Enyu Liu, Yunguang Li, Jun Niu, Changhai Li. Omi/HtrA2 pro-apoptotic marker differs in various hepatocellular carcinoma cell lines owing to ped/pea-15 expression level. Oncol Rep. 2015 Feb; 33(2): 905-912.

3. Mingming Hou, Xiaohui Guo, Yu Chen, Lidan Cong, Changwu Pan. A Prognostic Molecular Signature of N6-Methyladenosine Methylation Regulators for Soft-Tissue Sarcoma from The Cancer Genome Atlas Database. DATABASE ANALYSIS. 2020; 26: e928400-1-- e928400-13.

4. Yu Chen, Hui Zeng, Mingming Hou, Yuzhi Qiu. Azurin Regulates P21 and Enhances the Sensitivity of Osteosarcoma Cells to Cisplatin. Altern Ther Health Med. 2023 Oct;29(7):119-125.

5. Chen Yu; Chen Weigao; Yu ZhiHua. Clinical Analysis of 47 Cases of Osteosarcoma Around Knee Joint Treated with Inactivated Tumor Segment Replantation, Chongqing Medicine, 2012-10-20.

6. Chen Yu; Chen Weigao; Li. 58 Cases of Skin Defect Repair of Patients with Leg and Foot Malignant Melanoma after Operation, Chongqing Medicine,2012-08-30.

7. Chen Yu; Chen Weigao; Yu Zhihua. Analysis of 69 Cases of Surgical Treatment of Patients with Metastatic Bone Cancer of Four Limbs, Journal of Nanchang University (Medical Edition), 2012-09-30.

8. Chen Yu; Chen Weigao; Yu Zhihua. Analysis of Diagnosis and Treatment of 27 Cases of Primitive Neuroectodermal Tumor, Practical Clinical Medicine, 2011-02-20.

9. Chen Yu; Chen Weigao; Yu ZhiHua. Clinical Analysis of 112 Cases of Protuberant Dermatofibrosarcoma, Practical Clinical Medicine, 2011-01-20.

10. Chen Yu; Chen Weigao; Yu Zhihua. Clinical Analysis of Comprehensive Treatment of 61 Cases of Malignant Fibrous Histiocytoma, Jiangxi Medicine Journal, 2010-08-20.

11. Chen Yu; Chen Weigao; Yu Zhihua. Expression and Correlation of p21 and p16 genes in osteosarcoma, Journal of Jiangxi Medical College, 2009-06-30.

12. Chen Yu; Chen Weigao; Yu ZhiHua. Preliminary Study on the Expression and Correlation of p21 and p16 Genes in Osteosarcoma, Practical Clinical Medicine, 2005-11-30. 

13. Chen Yu; Chen Weigao; Yu ZhiHua. Clinical Analysis of 63 Cases of Synovial Sarcoma, Journal of Jiangxi Medical College, 2005-10-30.