Chen Yu, Director of the Department of Bone and Soft Tissue Surgery; Chief Physician; Class D High-Level Talent of Hainan Province; Master s degree in Orthopedic Surgery from Nanchang University School of Medicine. With over 30 years of clinical experience in orthopedics, Dr. Chen established the only department in Hainan dedicated to bone and soft tissue surgery, filling a gap in the treatment of bone and soft tissue tumors in the province. Under his leadership, the team has performed multiple high-difficulty procedures. Notably, they were the first in Hainan to carry out bone metastasis tumor resection combined with intraoperative radiotherapy and reconstruction, as well as the first expanded resection of limb soft tissue sarcoma with intraoperative radiotherapy and skin grafting.

He has participated in one national 863 Program project, served as the principal investigator for one provincial or ministerial-level project, led three projects funded by the Hainan Provincial Health Commission, and one by the Hainan Provincial Natural Science Foundation. He has published over 20 academic papers, including two in core Chinese journals and four in SCI-indexed journals.

I. Limb-sparing surgeries for malignant bone and soft tissue tumors, integrated with chemotherapy, radiotherapy, and intraoperative radiotherapy

II. Surgical and multimodal treatment of skin cancers such as melanoma

III. Surgical and comprehensive treatment of bone metastases

IV. Treatment of trauma, burns, joint disorders, spinal diseases, and osteopathies

Bone tumor, soft tissue tumor, skin tumor, bone metastatic cancer.

Currently served as: 
Ⅰ. Chairman of the Bone and Soft Tissue Tumor Professional Committee of Hainan Cancer Prevention and Treatment Association 
Ⅱ. Vice Chairman of Wound Repair Branch of Hainan Medical Association 
Ⅲ. Vice Chairman of Central South Bone Cancer Alliance of China Cancer Prevention Alliance 
Ⅳ. Standing Committee of Bone and Soft Tissue Oncology Group, Special Committee for Minimally Invasive Tumor Therapy, China Anti-Cancer Association 
Ⅴ. National member of Sarcoma Professional Committee of China Anti-Cancer Association 
Ⅵ. National member of Melanoma Professional Committee of China Anti-Cancer Association 
Ⅶ. National member of the Skin Cancer Professional Committee of China Anti-Cancer Association 
Ⅷ. National member of Bone and Soft Tissue Tumor Professional Committee, Chinese Medical Education Association 
Ⅸ. National member of Chemoradiotherapy Group, Sarcoma Professional Committee, China Anti-Cancer Association 
Ⅹ. Member of Orthopaedic Branch of Hainan Medical Association 
Ⅺ. Member of Pediatric Surgery Branch of Hainan Medical Association  
Once served as: 
Ⅰ. Member of the 9th National Youth Committee of Orthopaedic Branch of Chinese Medical Association 
Ⅱ. National member of SICOT Chinese Digital Orthopaedic Association, International Society for Orthopaedic and Trauma Surgery  
Ⅲ. Member of the First Sports Medicine Professional Committee of Hainan Medical Association 
Ⅳ. Member of Hand Surgery Branch of Hainan Medical Association 

1. ZONGQUAN XU, CHEN YU, SHUFANG WANG, and GUOHUI XU1, Transcatheter arterial chemoembolization as an examination method for hepatocellular carcinoma undetected by B-mode ultrasound, computed tomography and digital subtratcion angiography: A case report. Oncol Lett. 2015 Sep; 10(3): 1759–1762.

2.Zongquan Xu, Yu Chen, Guohui Xu, Cheng Peng, Enyu Liu, Yunguang Li, Jun Niu, Changhai Li. Omi/HtrA2 pro-apoptotic marker differs in various hepatocellular carcinoma cell lines owing to ped/pea-15 expression level. Oncol Rep. 2015 Feb; 33(2): 905-912.

3. Mingming Hou, Xiaohui Guo, Yu Chen, Lidan Cong, Changwu Pan. A Prognostic Molecular Signature of N6-Methyladenosine Methylation Regulators for Soft-Tissue Sarcoma from The Cancer Genome Atlas Database. DATABASE ANALYSIS. 2020; 26: e928400-1-- e928400-13.

4. Yu Chen, Hui Zeng, Mingming Hou, Yuzhi Qiu. Azurin Regulates P21 and Enhances the Sensitivity of Osteosarcoma Cells to Cisplatin. Altern Ther Health Med. 2023 Oct;29(7):119-125.

5. Chen Yu; Chen Weigao; Yu ZhiHua. Clinical Analysis of 47 Cases of Osteosarcoma Around Knee Joint Treated with Inactivated Tumor Segment Replantation, Chongqing Medicine, 2012-10-20.

6. Chen Yu; Chen Weigao; Li. 58 Cases of Skin Defect Repair of Patients with Leg and Foot Malignant Melanoma after Operation, Chongqing Medicine,2012-08-30.

7. Chen Yu; Chen Weigao; Yu Zhihua. Analysis of 69 Cases of Surgical Treatment of Patients with Metastatic Bone Cancer of Four Limbs, Journal of Nanchang University (Medical Edition), 2012-09-30.

8. Chen Yu; Chen Weigao; Yu Zhihua. Analysis of Diagnosis and Treatment of 27 Cases of Primitive Neuroectodermal Tumor, Practical Clinical Medicine, 2011-02-20.

9. Chen Yu; Chen Weigao; Yu ZhiHua. Clinical Analysis of 112 Cases of Protuberant Dermatofibrosarcoma, Practical Clinical Medicine, 2011-01-20.

10. Chen Yu; Chen Weigao; Yu Zhihua. Clinical Analysis of Comprehensive Treatment of 61 Cases of Malignant Fibrous Histiocytoma, Jiangxi Medicine Journal, 2010-08-20.

11. Chen Yu; Chen Weigao; Yu Zhihua. Expression and Correlation of p21 and p16 genes in osteosarcoma, Journal of Jiangxi Medical College, 2009-06-30.

12. Chen Yu; Chen Weigao; Yu ZhiHua. Preliminary Study on the Expression and Correlation of p21 and p16 Genes in Osteosarcoma, Practical Clinical Medicine, 2005-11-30. 

13. Chen Yu; Chen Weigao; Yu ZhiHua. Clinical Analysis of 63 Cases of Synovial Sarcoma, Journal of Jiangxi Medical College, 2005-10-30.