Chen Yu

Chief Physician

Skilled in limb-sparing surgery combined with chemoradiotherapy, intraoperative radiotherapy, and other comprehensive treatments for malignant bone tumors and soft tissue tumors, as well as surgery and comprehensive treatment for melanoma and other skin cancers, and surgery and comprehensive treatment for bone metastatic cancer.

Introduction of the expert

Chen Yu, Director of the Orthopedic Oncology Department, Chief Physician, High-level Top-notch Talent (Category D) in Hainan Province, and Masters degree holder in Orthopedic Surgery from Nanchang University Medical College. With over 30 years of clinical experience in orthopedics, he founded the only Orthopedic Oncology Department in Hainan Province, filling the gap in bone and soft tissue tumors in the province. During this period, he led the team to perform multiple high-difficulty surgeries, pioneering the first case of bone metastasis cancer resection + intraoperative radiotherapy + reconstruction in Hainan Province, and the first case of extensive resection of soft tissue sarcoma in the limbs + intraoperative radiotherapy + skin grafting in Hainan Province.

Participated in 1 national 863 project, led 1 provincial and ministerial level project, led 3 projects from the Provincial Health Department, and led 1 project from the Provincial Natural Science Foundation; published over 20 papers, including 2 in Chinese core journals and 4 SCI articles.

Medical specialty

I. Limb-sparing surgery for malignant bone tumors and soft tissue tumors, combined with comprehensive treatments such as chemoradiotherapy and intraoperative radiotherapy

II. Surgery and comprehensive treatment for skin cancer such as melanoma

III. Surgery and comprehensive treatment for bone metastatic cancer

IV. Treatment of trauma, burns, joints, spine, and bone diseases

Direction of scientific research

Bone tumors, soft tissue tumors, skin tumors, and metastatic cancer to the bone.

Academic association appointment

I. Director of the Melanoma Professional Committee of the Hainan Provincial Anti-Cancer Association

II. Head of the first batch of construction units in Hainan for the Melanoma Clinical Research Sub-center of the Chinese Anti-Cancer Association

III. National Committee Member of the Melanoma Professional Committee of the Chinese Anti-Cancer Association

IV. Vice Chairman of the Central South Bone Tumor Alliance of the China Cancer Prevention and Treatment Alliance

V. Chairman of the Bone and Soft Tissue Tumor Specialty Committee of the Hainan Provincial Cancer Prevention and Treatment Association

VI. Vice Chairman of the Wound Repair Branch of the Hainan Provincial Medical Association

VII. Vice Chairman of the Skin Tumor Professional Committee of the Hainan Provincial Anti-Cancer Association

VIII. Standing Committee Member of the Bone and Soft Tissue Tumor Group, Minimally Invasive Cancer Treatment Special Committee, Chinese Anti-Cancer Association

IX. National Committee Member of the Sarcoma Specialty Committee of the Chinese Anti-Cancer Association

X. National Committee Member of the Skin Tumor Professional Committee of the Chinese Anti-Cancer Association

XI. National Committee Member of the Bone and Soft Tissue Tumor Specialty Committee of the China Medical Education Association

XII. National Committee Member of the Radiotherapy and Chemotherapy Group of the Sarcoma Specialty Committee of the Chinese Anti-Cancer Association

XIII. Member of the Orthopedics Branch of the Hainan Provincial Medical Association

XIV. Member of the Pediatric Surgery Branch of the Hainan Provincial Medical Association

Papers and works

I. ZONGQUAN XU, CHEN YU (Chen Yu), SHUFANG WANG, and GUOHUI XU1, Transcatheter arterial chemoembolization as an examination method for hepatocellular carcinoma undetected by B-mode ultrasound, computed tomography and digital subtraction angiography: A case report. Oncol Lett. 2015 Sep;  10(3): 1759–1762.

II. Zongquan Xu, Yu Chen (Chen Yu), Guohui Xu, Cheng Peng, Enyu Liu, Yunguang Li, Jun Niu, Changhai Li. Omi/HtrA2 pro-apoptotic marker differs in various hepatocellular carcinoma cell lines owing to ped/pea-15 expression level. Oncol Rep. 2015 Feb; 33 (2): 905-912.

III. Mingming Hou, Xiaohui Guo, Yu Chen (Chen Yu), Lidan Cong, Changwu Pan. A Prognostic Molecular Signature of N6-Methyladenosine Methylation Regulators for Soft-Tissue Sarcoma from The Cancer Genome Atlas Database. DATABASE ANALYSIS. 2020; 26: e928400-1-- e928400-13

IV. Yu Chen, Hui Zeng, Mingming Hou, Yuzhi Qiu. Azurin regulates P21 and enhances the sensitivity of osteosarcoma cells to cisplatin. Altern Ther Health Med. 2023 Oct; 29(7):119-125.

V. Chen Yu, Chen Weigao, Yu Zhihua. Clinical Analysis of 47 Cases of Osteosarcoma around the Knee Joint Treated by Tumor Segment Inactivation and Replantation. Chongqing Medical Journal, 2012-10-20.

VI. Chen Yu, Chen Weigao, Li Jianqin. Repair of skin defects after malignant melanoma surgery in the lower leg and foot: a report of 58 cases. Chongqing Medical Journal, 2012-08-30.

VII. Chen Yu, Chen Weigao, Yu Zhihua. Analysis of Surgical Treatment for 69 Cases of Metastatic Cancer in Limbs. Journal of Nanchang University (Medical Edition), 2012-09-30.

VIII. Chen Yu, Chen Weigao, Yu Zhihua. Diagnosis and treatment analysis of 27 cases of primitive neuroectodermal tumor. Practical Clinical Medicine, 2011-02-20.

IX. Chen Yu, Chen Weigao, Yu Zhihua. Clinical Analysis of 112 Cases of Dermatofibrosarcoma Protuberans. Practical Clinical Medicine, January 20, 2011.

X. Chen Yu, Chen Weigao, Yu Zhihua. Clinical Analysis of Comprehensive Treatment for 61 Cases of Malignant Fibrous Histiocytoma. Jiangxi Medical Journal, 2010-08-20.

XI. Chen Yu, Chen Weigao, Yu Zhihua. Preliminary study on the expression and correlation of p21 and p16 genes in osteosarcoma. Journal of Jiangxi Medical University, 2009-06-30.

XII. Chen Yu, Chen Weigao, Yu Zhihua. Clinical Analysis of 92 Cases of Malignant Melanoma Treated with Comprehensive Therapy. Practical Clinical Medicine, 2005-11-30.

XIII. Chen Yu, Chen Weigao, Yu Zhihua. Clinical Analysis of 63 Cases of Synovial Sarcoma. Journal of Jiangxi Medical University, 2005-10-30.