Wei Zhixia

Chief Physician

Specializes in the comprehensive treatment of various malignant tumors such as head and neck malignant tumors, lung cancer, breast cancer, digestive tract tumors (liver cancer, stomach cancer, bowel cancer, etc.), urogenital system tumors (cervical cancer, ovarian cancer, bladder cancer, etc.), including chemotherapy, biological immunotherapy (molecular targeted therapy, cellular immunotherapy, etc.), endocrine therapy and traditional Chinese medicine. Based on MDT, she operated comprehensive treatment with neoadjuvant chemotherapy, postoperative adjuvant chemotherapy, and palliative chemotherapy as the main part. Has deep knowledge especially in the clinical and basic research of lung cancer and breast cancer. Committed to the medical treatment of cancer and the therapeutic research of molecular targeted drugs, and participated in and took charge of the introduction and clinical application of international anticancer drugs in the hospital.

Introduction of the expert

Chief physician, associate professor, other high-level talents in Hainan Province, postgraduate tutor. Has been engaged in clinical, teaching and research work of medical oncology for more than 30 years. Graduated from Southeast University and continued to study for a masters degree in the same university. Worked in the First Affiliated Hospital of Nanjing Medical University for 26 years and went to the Cancer Research Center of the University of Colorado for further study. Was selected by the Education Department of Jiangsu Province to study at the Cancer Research Center of the University of Colorado in the United States, and participated in the study and research of clinical trials of cancer drugs in Public Health School of Harvard University. At the same time, she also participated in a number of international and domestic multi-center clinical studies on gastric cancer and intestinal cancer as a main researcher. Undertook and participated in a number of scientific research projects in Jiangsu Province and Nanjing Medical University, mainly devoted to the study of the mechanism of multidrug resistance in tumor chemotherapy and the reversal of multidrug resistance. Many of her research results have been applied to clinical practice, and she published more than 30 academic papers.

Medical specialty

Specializes in the comprehensive treatment of various malignant tumors such as head and neck malignant tumors, lung cancer, breast cancer, digestive tract tumors (liver cancer, stomach cancer, bowel cancer, etc.), urogenital system tumors (cervical cancer, ovarian cancer, bladder cancer, etc.), including chemotherapy, biological immunotherapy (molecular targeted therapy, cellular immunotherapy, etc.), endocrine therapy and traditional Chinese medicine. Based on MDT, she operated comprehensive treatment with neoadjuvant chemotherapy, postoperative adjuvant chemotherapy, and palliative chemotherapy as the main part. Has deep knowledge especially in the clinical and basic research of lung cancer and breast cancer. Committed to the medical treatment of cancer and the therapeutic research of molecular targeted drugs, and participated in and took charge of the introduction and clinical application of international anticancer drugs in the hospital.

Direction of scientific research

Malignant tumor targeting and immunological therapy

Academic association appointment

Executive Chairman, Council of Hainan Tumor Control Association 
Member of the Third Council of Hainan Immunological Society 
Chairman of the Tumor Immunology Committee of Hainan Immunology Society 
Standing member of the Sixth Professional Committee of Oncology Branch of Hainan Provincial Medical Association 
Member of the Third Session of the Cancer Health Professional Committee of Hainan Anti-Cancer Association 
Standing member of Palliative Care Sub-Committee of Beijing Cancer Prevention and Treatment Research Association  
Standing member of the First session of the Breast Cancer Professional Committee of Hainan Cancer Prevention and Treatment Association 
Standing member of the First Session of the Colorectal Cancer Professional Committee of Hainan Cancer Prevention and Treatment Association 
Standing member of the First Committee of Tumor Immunity and Precision Therapy Professional Committee of Hainan Cancer Prevention and Treatment Association 
Standing member of the MDT Professional Committee of Hainan Cancer Prevention and Treatment Association 
Standing member of the First Committee of Lung Cancer Professional Committee of Hainan Cancer Prevention and Treatment Association 
Standing member of the Lung Cancer Specialized Committee of China Geriatric Healthcare Association 

Papers and works

1.Efficacy Observation of Oxaliplatin Combined with Calcium Folinate and Fluorouracil 5-fluorouracil in the Treatment of Advanced Gastric Cancer, Wei Zhixia. 
2.Reverse Effect of Tetramethylpyrazine on Multi-drug Resistant Strain SM7721_ADM in Liver Cancer, Wei Zhixia.
3.Clinical Study of Continuous Intravenous Infusion of High-dose CF 5-FU in the Treatment of Advanced Gastric Cancer, Wei Zhixia. 
4.Clinical Observation of Megestrol in the Treatment of Advanced Cancer Pain, Tian Ren, Wei Zhixia. 
5.Mechanism of Resistance to Adriamycin in Human Hepatocellular Carcinoma Cells Cultured in Vitro and Electron Microscopic Morphology, Liu Shunying, Wei Zhixia. 
6.Reversal of Ultidrug Resistance in Hepatocellular Carcinoma Cells by Isobodin, Liu Shunying, Wei Zhixia. 
7.Observations on the Efficacy and Toxicity of FOLFIRI Regimen Chemotherapy in Patients with Advanced Colorectal cancer, Zhang Xiangwei, Wei Zhixia. 
8.Alteration of Electron Microscopic Morphology in Induced Drug Resistance Culture of SMMC-7721 Cells, Wei Zhixia. 
9.P-glycoprotein Changes in Induced Drug Resistance Culture of SMMC-7721 Cells, Wei Zhixia.  
10.Reversal and Mechanism of Multidrug-resistant Strain. in Hepatocellular Carcinoma by α-interferon, Wei Zhixia. 
11.Study on Reversal of Drug Resistance in Hepatocellular Carcinoma Cells by α-interferon and Isoptin, Liu Shunying, Wei Zhixia. 
12.Pingping Ai, Xianhua Xu, Shijie Xu, Zhixia Wei, Shun Tan, Junzhe Li, Overexpression of Wnt7a enhances radiosensitivity of non-small-cell lung cancer via the Wnt/JNK pathway.
13.Xianhua Xu, Shijie Xu, Zhixia Wei, Junzhe Li, Wnt7a inhibits transformed cell proliferation while promoting migration and invasion in non-small cell lung cancer.