Wei Zhixia

Chief Physician

Specializes in the comprehensive treatment of various malignant tumors such as head and neck malignant tumors, lung cancer, breast cancer, digestive tract tumors (liver cancer, stomach cancer, bowel cancer, etc.), urogenital system tumors (cervical cancer, ovarian cancer, bladder cancer, etc.), including chemotherapy, biological immunotherapy (molecular targeted therapy, cellular immunotherapy, etc.), endocrine therapy and traditional Chinese medicine. Based on MDT, she operated comprehensive treatment with neoadjuvant chemotherapy, postoperative adjuvant chemotherapy, and palliative chemotherapy as the main part. Has deep knowledge especially in the clinical and basic research of lung cancer and breast cancer. Committed to the medical treatment of cancer and the therapeutic research of molecular targeted drugs, and participated in and took charge of the introduction and clinical application of international anticancer drugs in the hospital.

Introduction of the expert

Chief physician, associate professor, other high-level talents in Hainan Province, postgraduate tutor. Has been engaged in clinical, teaching and research work of medical oncology for more than 30 years. Graduated from Southeast University and continued to study for a masters degree in the same university. Worked in the First Affiliated Hospital of Nanjing Medical University for 26 years and went to the Cancer Research Center of the University of Colorado for further study. Was selected by the Education Department of Jiangsu Province to study at the Cancer Research Center of the University of Colorado in the United States, and participated in the study and research of clinical trials of cancer drugs in Public Health School of Harvard University. At the same time, she also participated in a number of international and domestic multi-center clinical studies on gastric cancer and intestinal cancer as a main researcher. Undertook and participated in a number of scientific research projects in Jiangsu Province and Nanjing Medical University, mainly devoted to the study of the mechanism of multidrug resistance in tumor chemotherapy and the reversal of multidrug resistance. Many of her research results have been applied to clinical practice, and she published more than 30 academic papers.

Medical specialty

Specializes in the comprehensive treatment of various malignant tumors such as head and neck malignant tumors, lung cancer, breast cancer, digestive tract tumors (liver cancer, stomach cancer, bowel cancer, etc.), urogenital system tumors (cervical cancer, ovarian cancer, bladder cancer, etc.), including chemotherapy, biological immunotherapy (molecular targeted therapy, cellular immunotherapy, etc.), endocrine therapy and traditional Chinese medicine. Based on MDT, she operated comprehensive treatment with neoadjuvant chemotherapy, postoperative adjuvant chemotherapy, and palliative chemotherapy as the main part. Has deep knowledge especially in the clinical and basic research of lung cancer and breast cancer. Committed to the medical treatment of cancer and the therapeutic research of molecular targeted drugs, and participated in and took charge of the introduction and clinical application of international anticancer drugs in the hospital.

Direction of scientific research

Malignant tumor targeting and immunological therapy

Papers and works

1. Reverse Effect of Tetramethylpyrazine on Multi-drug Resistant Strain SMMC-7721/ADM in Liver Cancer

2. P-glycoprotein Changes in Induced Drug Resistance Culture of SMMC-7721/ADM Cells

3. Alteration of Electron Microscopic Morphology in Induced Drug Resistance Culture of SMMC-7721/ADM Cells

4. Reversal and Mechanism of Multidrug-resistant Strain SMMC-7721/ADM in Hepatocellular Carcinoma by α-interferon

5. Study on Reversal of Drug Resistance in Hepatocellular Carcinoma Cells by α-interferon and Isoptin

6. Clinical Study of Continuous Intravenous Infusion of High-dose CF + 5-FU in the Treatment of Advanced Gastric Cancer

7. Efficacy Observation of Oxaliplatin Combined with Calcium Folinate and 5-FU in the Treatment of Advanced Gastric Cancer

Accomplished Project:

1. Study on the Reversal of Drug Resistance of Ligustrazine on Liver Cancer

2. Study on Ribozyme Cutting FOS Gene to Reverse Multi-drug Resistance in Hepatocellular Carcinoma Cells

3. Study on the Combination of Chemotherapy Drugs and Isopodine in the Treatment of Cancerous Ascites

Academic position

Standing member of the 5th Oncology Professional Committee of Hainan Medical Association

Member of the third Session of the Cancer Health Professional Committee of Hainan Anti-Cancer Association

Standing member of Palliative Care Sub-Committee of Beijing Cancer Prevention and Treatment Research Association

Member of Immunological Sub-committee of Beijing Cancer Prevention and Treatment Research Association

Executive Director of the first Council of Hainan Cancer Prevention and Treatment Association

Standing member of the first session of the Breast Cancer Professional Committee of Hainan Cancer Prevention and Treatment Association

Standing member of the first Session of the Colorectal Cancer Professional Committee of Hainan Cancer Prevention and Treatment Association

Standing member of the first Committee of Tumor Immunity and Precision Therapy Professional Committee of Hainan Cancer Prevention and Treatment Association

Vice Chairman of the Tumor Immunology Committee of the third Council of Hainan Immunology Society

Member of the third Council of Hainan Immunological Society

Standing member of the MDT Professional Committee of Hainan Cancer Prevention and Treatment Association

Standing member of the 4th Committee of Oncology Professional Committee of Hainan Medical Association