"I used to have to travel off the island for follow-up exams, which was a hassle and cost a lot in travel expenses. Now, I can get a full set of tests in Haikou, and there are also targeted treatment plans afterwards. It's really great!" Mr. Liu, who lives in Sanya, held the newly received P-tau217 test report and spoke highly of Hainan Chengmei Hospital's early screening and diagnosis and treatment program for Alzheimer's disease (AD, also known as senile dementia).
Alzheimer's disease is a degenerative disease of the central nervous system, and once clinical symptoms appear, they are irreversible. Therefore, the whole-process management of early screening, precise diagnosis, and scientific intervention is particularly crucial.
Hainan Chengmei Hospital has deeply delved into the field of Alzheimer's disease diagnosis and treatment, establishing a precise screening system that combines "blood testing + dual PET-CT imaging detection". It has achieved a one-stop closed-loop service covering "screening - diagnosis - staging - treatment", providing patients with comprehensive medical care from early intervention to drug therapy.
In the detection and diagnosis phase, the hospital has established a dual precision system of "biomarkers + imaging localization". Blood tests cover four internationally recognized core biomarkers: Aβ42, Aβ40, P-tau181, and P-tau217. Through a simple blood draw, the deposition of amyloid protein and neuronal damage in the brain can be quickly assessed, providing an important reference for early risk warning. On this basis, PET-CT testing further covers two core items: AβPET and tauPET, which can visually present the distribution and density of amyloid plaques and tau tangles in the brain, providing a "gold standard" basis for the diagnosis and biological staging of Alzheimer's Disease (AD), making disease assessment more precise and treatment plans more targeted.
The hospital has established a specialized memory clinic, staffed by experienced physicians, providing one-stop services from initial consultations, risk assessments, comprehensive testing, biological staging, to personalized interventions. The outpatient department will develop an exclusive diagnosis and treatment plan based on the patient's age, medical history, cognitive function status, and test results; At the same time, for patients who meet the indications, hospitals can provide special treatment drugs including lencanavir monoclonal antibody, providing more effective treatment options for patients with rapid disease progression or high risk.
"I used to think that Hainan couldn't provide such professional testing. I never thought that now, not only can local hospitals in Hainan complete accurate screening and staging, but they can also use targeted special drugs. This not only saves the trouble of traveling back and forth, but also makes the cost more affordable," Mr. Liu said with emotion. He hopes that more patients like him can know this good news and no longer have to travel far away for the diagnosis and treatment of Alzheimer's disease.
With the acceleration of population aging, the demand for the prevention and treatment of Alzheimer's Disease (AD) is becoming increasingly urgent. Director Dai Wenxin, an expert at the Memory Clinic of the hospital, stated that they will continue to optimize the AD diagnosis and treatment service chain, continuously improve the accuracy of detection technology and the standardization level of diagnosis and treatment, and provide more convenient, professional, and comprehensive medical care for the elderly population in Hainan and surrounding areas through the full-process service of "precise screening + scientific staging + targeted treatment", enabling more patients to achieve "early detection, precise diagnosis, and effective intervention".
Expert Introduction
Dai Wenxin, Chief Physician
Executive Director of the Multidisciplinary Geriatrics Diagnosis and Treatment Center
Professor, doctoral candidate
Postdoctoral researcher, master's supervisor
Medical expertise:
I. Diagnosis and treatment of Alzheimer's disease and other geriatric diseases
II. Diagnosis and treatment of diseases across multiple disciplines, including respiratory system, cardiovascular system, nervous system, and geriatric diseases
III. Genetic diagnosis, chemotherapy, targeted therapy, immunotherapy, microenvironment analysis, and integrated precision treatment of tumors
IV. Genetic diagnosis and precision treatment of hypertension, hyperlipidemia, hyperuricemia, and hyperglycemia
V. New biomedical technologies such as stem cells and gene programming, as well as new technologies like insulin pumps and diabetes reversal
VI. High-intensity focused ultrasound (HIFU) for treating benign and malignant tumors
VII. Microbial therapy of intestinal flora for chronic diseases and mental and psychological disorders
VIII. Diagnostic and therapeutic techniques under medical endoscopes such as bronchoscope, mediastinoscope, and thoracoscope
IX. Sleep medicine
X. Chronic disease management
Article | Huang Fei