For
Ms. Fang, who is 60 years old, the battle against lung cancer has lasted for
nearly four years. It has been a thorny journey, involving targeted therapy,
adverse drug reactions, and multiple adjustments to treatment plans. When the
latest monitoring indicators once again show red lights, confusion and anxiety
inevitably arise in her heart.
In September 2025, she chose to seek consultation from Professor Yang Nong, an expert in lung cancer diagnosis and treatment and a specially-appointed expert at Hainan Cancer Hospital, hoping to find a clear and firm answer for her subsequent treatment.
Four Years of Fighting Cancer: Maintaining Balance Amidst Setbacks
In November 2021, Ms. Fang was diagnosed with lung adenocarcinoma with pleural metastasis and began receiving targeted drug therapy.
However, shortly after taking the medication, she developed significant adverse drug reactions: new costochondral destruction and a continuous increase in pleural effusion. The physical discomfort forced her to suspend the current regimen and switch to a different targeted drug.
In early 2024, a follow-up CT scan confirmed interstitial pneumonia. After changing the medication again, due to extremely poor physical tolerance, the treatment was suspended after only one month, and the patient switched to closely monitoring the progression risk through MRD (minimal residual disease) monitoring, which became the "balance line" for maintaining stable disease.
In March 2025, this fragile balance was once again disrupted: the MRD monitoring results turned positive, and the risk of disease progression soared. Ms. Fang had to initiate targeted therapy again, which has continued to this day.
The protracted battle over the past four years has left her and her family physically and mentally exhausted, and they urgently need an authoritative expert to clear up the confusion surrounding their condition.
Accurate judgment: clearing the clouds from the mind
Through a friend's recommendation, Ms. Fang became interested in Professor Yang Nong, who has extensive experience in the field of lung cancer diagnosis and treatment. She firmly believes that Professor Yang Nong's health education on social media can provide her with the answers she wants.
During the consultation, Professor Yang Nong patiently reviewed Ms. Fang's complex medical history spanning four years and provided an extremely clear assessment of her current condition.
"Currently,
the MRD test indicates persistent positivity with an increasing trend, which
indeed signifies an escalating treatment pressure, necessitating further
intensified intervention." Professor Yang Nong first objectively pointed
out the current risks, "On the basis of existing targeted therapy,
combining chemotherapy or anti-vascular targeted therapy may better control
disease progression."
As soon as the words fell, Professor Yang Nong changed his tone, pointing to the latest imaging film and saying with certainty, "But look here - the pleural effusion has completely subsided, and the problem of pleural thickening has also been resolved. This is a very crucial signal, indicating that the previous treatment plan is effective and the core lesion has been controlled. We don't need to be overly anxious."
This analysis, which contained both risk warnings and positive signals, was like a "shot in the arm" for Ms. Fang and her family. Professor Yang Nong not only clarified the direction of the next step of treatment but also confirmed the achievements of previous treatments with solid imaging evidence, dispelling the panic and confusion that had hung over them.
This clarity and certainty also put Ms. Fang completely at ease. "After hearing Professor Yang's words, my mind suddenly became clear!" Ms. Fang could not conceal her gratitude, "He not only told us how to proceed, but also made us clearly understand what our condition really is. This sense of reassurance gave me the confidence and determination to keep going."
Expert Introduction
Yang Nong
Chief Physician, Doctoral Supervisor
Long-term employed experts of Hainan Cancer Hospital and Hainan Chengmei Hospital
He currently serves as Vice President of the Second People's Hospital of Hunan Province, head of the oncology department, and director of the "Yang Nong Famous Doctor Clinic" / "Yang Nong Famous Doctor Expert Team Clinic". He is also a chief expert of the National Major Scientific and Technological Special Project, a member of the Lung Cancer Special Committee of the National Tumor Quality Control Center, the director of the Hunan Provincial Key Laboratory of Precision Diagnosis and Treatment of Lung Cancer, and the director of the Hunan Provincial Respiratory Tumor Clinical Medical Research Center. He has been dedicated to precision targeted therapy for lung cancer and gastrointestinal tumors, as well as to clinical, scientific research, and teaching work related to difficult, recurrent, and drug-resistant cases for nearly 30 years.
He has been honored with the title of "National Famous Doctor - Excellent Style" in the 6th edition, and has been recommended by patients across the country as "Annual Good Doctor" for 8 consecutive years, as well as being awarded the title of "First Brain Doctor - Famous Doctor". He has authored national guidelines, boasts over 500,000 followers across the internet, and has achieved over 120 million views on his anti-cancer science popularization videos.
Medical expertise
Specialties: Precision treatment of lung cancer, breakthrough in refractory, recurrent, and drug-resistant cases with brain metastasis; individualized and precise treatment of brain metastases from lung cancer; early diagnosis of pulmonary nodules and lung cancer; personalized comprehensive diagnosis and treatment of solid tumors; clinical trials of the latest immunotherapy/targeted therapy drugs.
·With nearly 30 years of experience in precision immunotherapy for lung cancer, he has led nearly 400 phase I-III clinical trials of new anticancer drugs (including national Class 1 new drugs), and is particularly skilled in treating complex cases such as refractory, recurrent, and drug-resistant conditions, as well as brain metastases.
·Early diagnosis and treatment of pulmonary nodules and lung cancer, with an annual diagnosis of over 2,000 cases (over 10,000 cases accumulated from 2019 to 2024), and a detection rate of over 90% (retrospective study in 2023).
·Proficient in comprehensive diagnosis and treatment of multiple cancer types, individualized, and interdisciplinary, covering pan-solid tumors (such as stomach/intestine/brain, etc.).
·Professor Yang Nong receives over 14,000 visits annually (2023 data).
·Managing the "Lung Cancer Immunotherapy Patient Group", with long-term follow-up management of over 4,000 lung cancer patients who have achieved long-term survival, accumulating rich clinical experience.
[Visit information]
01 [Visit Time and Location]
8:00-12:00 on November 22nd
The sixth consultation area of Hainan Cancer Hospital
02 [Appointment registration]
Follow the official account of Hainan Cancer Hospital for "appointment registration"
03 [Health Consultation]
13876807106
04 [Friendly Reminder]
To facilitate the experts in understanding your condition as soon as possible, please bring:
1. ID card, medical insurance card, mobile phone
2. Accompany immediate family members (with decision-making authority)
3. Arrange the relevant examinations you have undergone in chronological order
4. Paper medical records of previous visits
5. Surgical case biopsy: paraffin blocks or 20-30 white slides
6. Pathological diagnosis report
7. Inpatient medical records and notes
8. Recent relevant examinations
9. The patient's current treatment plan
10. The most pressing questions I want to inquire about