
Mr. Wan, 60 years old, is from Heilongjiang and was diagnosed with lung cancer a year ago.
After a year of treatment, the results of the follow-up examination made his heart tense.
Now settled in Hainan, he, upon the recommendation of a fellow patient, brought his medical records to the consultation room of Professor Yang Nong, a specially-appointed expert at Hainan Cancer Hospital/Affiliated Cancer Hospital of Hainan Medical University
From depression to starting anew
In May 2025, Mr. Wan sought medical attention due to lung discomfort and was suspected to have lung cancer. He underwent CT-guided percutaneous lung biopsy and was diagnosed with invasive adenocarcinoma. Upon receiving the diagnosis, Mr. Wan fell into a state of depression and found it difficult to sleep and eat. With the encouragement of his family, he gradually adjusted his mindset and started targeted therapy.
However, a year later, a follow-up chest CT scan revealed that the tumor in the upper lobe of the lung had slightly increased in size compared to before. Although the lesion had not grown significantly, Mr. Wan and his family were once again on tenterhooks. The attending doctor had recommended continuing to take oral targeted drugs and follow-up observations, but Mr. Wan remained apprehensive.
After Mr. Wan and his family relocated to Hainan, they sought out various options for a better follow-up treatment plan. Through recommendations from fellow patients, they learned that Professor Yang Nong had extensive clinical experience, enjoyed a good reputation among patients, and regularly visited Hainan for consultations. After extensive inquiries, the family decided to seek treatment from him.
"Finally found the right person"
In September this year, accompanied by his family, Mr. Wan walked into Professor Yang Nong's consulting room.
Professor Yang Nong carefully reviewed the patient's medical records from over a year ago and compared the images one by one. Professor Yang explained the condition to the patient: "Currently, single-drug targeted therapy is being used, but the imaging suggests a slow increase in the size of the lesion. It is recommended to add drugs to the existing regimen and carry out combination therapy."

Professor Yang Nong on duty (file photo)
He further analyzed the images and said, "Based on your overall condition and the latest images, radiotherapy can be administered to the pulmonary lesions and their draining areas for precise local treatment." Seeing Mr. Wan's nervous expression, Professor Yang patiently reassured him, "With your current physical condition, there is no need for excessive anxiety. We employ a gentle treatment approach, and the side effects are relatively manageable, with most of the body being able to tolerate them."
"After my father was diagnosed, we were constantly searching for the right treatment plan, and we were never sure," Mr. Wan's son said with emotion. "Professor Yang explained my father's condition clearly and thoroughly, and we felt at ease immediately. We finally felt like we had found the right person!"
Expert reminder
Professor Yang Nong stated that slow progression of lesions does not necessarily mean that targeted drugs have completely lost their effectiveness, and there is no need to blindly switch to another drug.
Such patients can be evaluated for comprehensive treatment strategies, including targeted therapy combined with local radiotherapy, based on lesion changes, genetic status, and physical tolerance.
Implementing precise radiotherapy for isolated or oligometastatic lesions can effectively control local tumors, prolong the use of targeted drugs, and simultaneously maintain quality of life.
He reminded lung cancer patients to adhere to standardized follow-up examinations during targeted therapy. Once any changes in the lesion are detected, it is recommended to visit a specialist outpatient clinic for multidimensional evaluation and to develop a personalized follow-up plan. Patients should never stop or adjust their medication on their own.
Expert Introduction

Yang Nong, Chief Physician, Doctoral Supervisor
Long-term employed experts from Hainan Cancer Hospital/Affiliated Cancer Hospital of Hainan Medical University and Hainan Chengmei Hospital
He currently serves as Vice President of the Second People's Hospital of Hunan Province, head of the oncology department, and director of the "Yang Nong Famous Doctor Clinic" / "Yang Nong Famous Doctor Expert Team Clinic". He is also a chief expert of the National Major Scientific and Technological Special Project, a member of the Lung Cancer Special Committee of the National Tumor Quality Control Center, the director of the Hunan Provincial Key Laboratory of Precision Diagnosis and Treatment of Lung Cancer, and the director of the Hunan Provincial Respiratory Tumor Clinical Medicine Research Center. He has been dedicated to precision targeted therapy for lung cancer and gastrointestinal tumors, as well as to challenging, recurrent, and drug-resistant clinical cases, scientific research, and teaching for nearly 30 years.
He has been honored with the title of "National Famous Doctor - Excellent Style" in the 6th edition, and has been recommended as "Annual Good Doctor" by patients across the country for 8 consecutive years, as well as being awarded the title of "First Brain Doctor - Famous Doctor". He has authored national guidelines, boasts over 500,000 followers across the internet, and has achieved over 120 million views in cancer prevention and treatment science popularization.
Medical expertise
Specialties: Precision treatment of lung cancer, breakthrough in refractory, recurrent, and drug-resistant cases with brain metastasis; individualized and precise treatment of brain metastases from lung cancer; early diagnosis of pulmonary nodules and lung cancer; personalized and comprehensive diagnosis and treatment of solid tumors; clinical trials of the latest immunotherapy/targeted therapy drugs.
With nearly 30 years of experience in precision immunotherapy for lung cancer, he has led nearly 400 Phase I-III clinical trials of new anticancer drugs (including Class 1 national new drugs), and is particularly skilled in treating complex cases such as refractory, recurrent, and drug-resistant conditions, as well as brain metastases.
He is also proficient in the comprehensive diagnosis and treatment of multiple cancer types, individualized, and interdisciplinary, covering a wide range of solid tumors (such as stomach, intestine, brain, etc.).
[Visit Information]
1. Clinic Hours and Location
September 27th, 08:00-12:00
Sixth Consultation Area of Hainan Cancer Hospital
2. [Appointment registration]
Follow the official account of Hainan Cancer Hospital for "appointment registration"
3. Health consultation
18976324546
[Friendly Reminder]
To help the expert understand your condition quickly, please bring the following:
1. ID card, medical insurance card, and mobile phone
2. Accompanying direct relatives (with decision-making authority)
3. Relevant previous examination results, organized chronologically
4. Paper medical records from previous consultations
5. Surgical case slides, wax blocks, or 20-30 glass slides
6. Pathological diagnosis report
7. Hospitalization medical records
8. Recent relevant examination results
9. The patients current treatment plan
10. The most urgent questions to consult